NCT01516307

Trial of Active Immunotherapy With Globo H-KLH (OPT-822) in Metastatic Breast Cancer Subjects

Conditions: Metastatic Breast Cancer
Sponsors: Optimer Biotechnology, Inc.
Phase II

NCT01498328

A Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastoma (ReACT)

Conditions: Glioblastoma, Small Cell Glioblastoma, Giant Cell Glioblastoma, Gliosarcoma, Glioblastoma With Oligodendroglial Component
Sponsors: Celldex Therapeutics
Phase II

NCT01480479

Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma (ACT IV)

Conditions: Glioblastoma, Small Cell Glioblastoma, Giant Cell Glioblastoma, Gliosarcoma, Glioblastoma With Oligodendroglial Component
Sponsors: Celldex Therapeutics
Phase III

NCT01426828

Id-KLH Vaccine + T Cells

Conditions: Multiple Myeloma
Sponsors: Abramson Cancer Center of the University of Pennsylvania
Phase II

NCT01349647

Immunization With a Pentavalent Vaccine Composed of KLH-conjugates of GD2L, GD3L, Globo H, Fucosyl GM1, and N-Propionylated Polysialic Acid

Conditions: Lung Cancer
Sponsors: Memorial Sloan-Kettering Cancer Center, National Cancer Institute (NCI)
Phase: n/a 

2010-019996-32

A Phase II, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Clinical Efficacy, Safety and Immunogenicity of Neovacs’ TNFα-Kinoid in Adult Subjects with Crohn’s Disease

Conditions: Crohn’s Disease
Sponsors: Neovacs SA
Phase II

NCT01291810

Clinical Efficacy of TNFa Kinoid in Crohn's Disease Patients

Conditions: Crohn's Disease
Sponsors: Neovacs
Phase II

NCT01250470

Survivin Vaccine Therapy for Patients With Malignant Gliomas

Conditions: Adult Anaplastic Astrocytoma, Adult Anaplastic Oligodendroglioma, Adult Giant Cell Glioblastoma, Adult Glioblastoma, Adult Gliosarcoma, Adult Mixed Glioma, Recurrent Adult Brain Tumor
Sponsors: Roswell Park Cancer Institute
Phase I

NCT01248273

Unimolecular Pentavalent (Globo-H-GM2-sTn-TF-Tn) Immunization of Patients With Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer in First Remission

Conditions: Fallopian Tubes, Ovarian Cancer, Peritoneal Cancer
Sponsors: Memorial Sloan-Kettering Cancer Center
Phase I

NCT01223235

Polyvalent Vaccine-KLH Conjugate + Opt-821 Given in Combination With Bevacizumab

Conditions: Fallopian Tube Cancer, Ovarian Cancer, Peritoneal Cancer
Sponsors: Memorial Sloan-Kettering Cancer Center, Genentech
Phase n/a